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Year : 2022  |  Volume : 6  |  Issue : 5  |  Page : 7-10

Point-of-care thromboelastography, rotational thromboelastometry during extracorporeal membrane oxygenation

Department of Intensive Care Service, Prince Sultan Military Medical City, Riyadh, Saudi Arabia

Correspondence Address:
Abdullah M Abudayah
Department of Intensive Care Service, Prince Sultan Military Medical City, Riyadh
Saudi Arabia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2543-1854.369159

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Extracorporeal membrane oxygenation (ECMO) has been used increasingly for both respiratory and cardiac failure in adult patients. The patients requiring ECMO are at increased risk of developing significant coagulopathy. The exposure of a patient's blood to the artificial surface of the ECMO circuit results in the activation of the coagulation-fibrinolysis system and an inflammatory response. During ECMO, anticoagulation is required to prevent thrombotic complications, and unfractionated heparin (UFH) remains the predominant anticoagulation agent used to minimize the potentially life-threatening complications related to bleeding events or thromboembolic complications. Most centers adjust UFH by activated clotting time (ACT) of 140–180 sec or partial thromboplastin time (PTT) of 40–80 s. In this article, we will review thromboelastometry use during ECMO in ICU.

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